Agios Nikólaos (GR: Αγιος Νικόλαος), with 9.500 inhabitants, is the capital of the Lassithi province of Crete. It is built around a picturesque lake at the north-western side of the Mirabello bay, the biggest bay in Crete. Major administrative, cultural and communications center, Agios Nikolaos is one of the most developed tourist areas, not only in Crete but in Greece in general. Thanks to the beautiful coasts, the great sights and the cosmopolitan life, this lively city hosts every year thousands of visitors without losing one bit of its tranquility and traditional hospitality.

The island of Spinalonga (Gr: Σπιναλόγκα), officially known as Kalydon (Καλυδών), is located in the Gulf of Elounda in north-eastern Crete, in Lasithi prefecture, next to the town of Elounda. The official Greek name of the island today is Kalydon. Originally, Spinalonga was not an island, it was part of the island of Crete. During Venetian occupation the island was carved out of the coast for defense purposes and a fort was built there. A popular name for the island since Venetian rule is Spinalonga. During Venetian rule, salt was harvested from salt pans around the island. The island has also been used as a leper colony. Spinalonga has appeared in novels, television series, and a short film.

The area is touristic developed with many shops, restaurants on the shore, bars and several excellent hotels famous for their comforts and the variety of amenities offered. The lagoon of Elounda is shaped between the coast and a small peninsula of 7-8 km length ... Spinalonga, since antiquity, has protected the harbor of ancient Olous.

The village of Sissi, a picturesque village 40 km east of Heraklion and 25 km west of Ag. Nikolaos. Sissi is a beautiful fishing village with strange nature. On one side of the village the nature is wild, with a small river flowing into the sea, a number of palm trees on its banks, ducks and geese swimming peacefully. On the other side there are sandy and gravel beaches, caverns in the rocks and deep clear water, full of many kinds of fish. A place that gathers the nature of different places of Crete.

Neapolis is located 15 km westwards of Agios Nikolaos on the way to Heraklion from where it is roughly 50 km far. Neapolis is built in the green valley of Mirabello.
In the period of the Venetian domination its two settlements were named "New Village". But when the seat of the Prefecture was transferred from Fourni to the “New Village” this last was renamed to Neapolis. Neapolis was maintained as the capital of the prefecture of Lasithi till 1904. After that date Agios Nikolaos became the new capital.

Lato (Gr: Λατώ) was an ancient city of Crete, the ruins of which are located approximately 3 km from the small town of Kritsa. The Dorian city-state was built in a defensible position overlooking Mirabello Bay between two peaks, both of which became acropolises to the city. Although the city probably predates the arrival of the Dorians, the ruins date mainly from the Dorian period (fifth and fourth centuries BC). The city was destroyed ca. 200 BCE, but its port (Lato Etera or Lato pros Kamara), located near Agios Nikolaos was in use during Roman rule.
There is some suggestion that the city was named after the goddess Leto (of which Lato is the usual Doric form) and may be mentioned in Linear B tablets as RA-TO. Lato also minted coins in antiquity,[3] bearing the likeness of the goddess Eileithyia who appears to have been the one particularly worshipped at Lato.
Nearchus, admiral of Alexander the Great, was born at Lato.

Kritsa is one of the most picturesque towns in Crete, built amphitheatrically on a rock hill. It is located 11 km from Agios Nikolaos and has 2000 inhabitants. The people keep the old Cretan customs and the traditions and the town is considered one of the most important centers of the Cretan folk and weaving art.

The Panagia Kera of Kritsa, as it is called the Temple of the Virgin Mary (Kera), is 1 km to the north of the village of Kritsa in Merabello Lassithi, in a place called Logari, right on the road from Agios Nikolaos to Kritsa. The history of the church of Panayia Kera begins at least since the 13th century.

Near the beautiful village of Vrahasi there is the imposing gorge of Selinari, formed by the mountain of Anavlohos (625 m) to the north and the mountain Fonias o Detis (818 m) to the south. The symbol of Crete, the Cretan wild goat (Agrimi or kri-kri) and the Griffon Vulture are two rare species that used to reside in the gorge. The authorities in Vrahasi intend to establish a center of protection of the local fauna and flora at the gorge of Selinari and to develop a wildlife station, to provide observation of the Griffon Vulture colony at the east side of the gorge of Selinari. The hunting is forbidden in an area covering 10 sq.km. around the gorge.

At the side of the gorge of Selinari, at the 42 km. of the national road Iraklion - Agios Nikolaos is the small old chapel and the newly founded monastery of Agios Georgios Selinaris. In the monastery there is also a home for the aged founded in 1963. The small chapel was probably founded early in the 16th century AD, and ever since it is a place of worshiping. The people passing through the chapel stop to light a candle to the saint. The chapel is considered miraculous, there are various legends concerning miracles related either with healing of sick people or with divine punishment of people that did not pay the respect due to the saint.

The Archaeological Museum of Aghios Nikolaos is one of the most important in Crete and has been in operation since 1969. It houses collections of very important archaeological finds from the whole of Eastern Crete, an area extending from Malia as far as Zakros. These are displayed in chronological order from the Neolithic period (5700 - 2800 B.C.) to the end of the Roman times (100 B.C. - 400 A.D.) Its showcases include more than 1350 vases from the 3rd millennium B.C. as well as gold and copper finds (the most ancient found in Crete).

Vrahasi is an old Cretan village, built amphitheatrically at the slope of the mountain Anavlohos (alt. 625m) with an excellent view towards the Lasithiotika mountains and the gorge of Selinari.